BiochemistryNucleic Acids ResearchPeer-reviewed
Molecular basis of UV lesion binding and repair inhibition by ETS-family transcription factors
Smitha Sivapragasam, James Ross Terrell, Arjan van der Vaart…·Gregory M.K. Poon
This study investigates how ETS-family transcription factors bind to UV-damaged DNA and inhibit repair, revealing structural and dynamic differences that explain mutation hotspots in melanoma.
DOI 10.1093/nar/gkag711