Author

Sérgio Oliveira de Paula

Universidade Federal de ViçosaORCID 0000-0002-2275-5768Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Assay:metagenomics· 1 Organism:non-human primate· 1 Research Focus:protein design· 1 Assay:protein structure· 1

Frequent Co-Authors

Adriele Jéssica do Carmo SantosiD· 1 shared Alan Emanuel Silva CerqueiraiD· 1 shared Amanda Tristão SantiniiD· 1 shared Cynthia Canêdo da SilvaiD· 1 shared Gabriel Luz WallauiD· 1 shared Helder Canto ResendeiD· 1 shared Isabelle F. T. VianaiD· 1 shared Matheus Vitor Ferreira FerraziD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiophysics

Adriele Jéssica do Carmo SantosORCID

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2 papers

Recent·Most cited

Gut microbiota of Brazilian Melipona stingless bees: dominant members and their localization in different gut regions

Amanda Tristão Santini, Alan Emanuel Silva Cerqueira, Nancy A. Moran, Helder Canto Resende, Weyder Cristiano Santana, Sérgio Oliveira de Paula, Cynthia Canêdo da Silva

The paper identifies dominant gut microbiota members in Melipona stingless bees and their localization across gut regions, showing spatial organization similar to other eusocial bees.

bioRxiv · Jun 3, 2025 · PreprintMicrobiology

Design of nanobody targeting SARS-CoV-2 spike glycoprotein using CDR-grafting assisted by molecular simulation and machine learning

Matheus Vitor Ferreira Ferraz, Wenny Camilla dos Santos Adan, Tayná Evily de Lima, Adriele Jéssica do Carmo Santos, Sérgio Oliveira de Paula, Rafael Dhália, Gabriel Luz Wallau, Rebecca C. Wade, Isabelle F. T. Viana, Roberto Dias Lins

This paper designs a high-affinity nanobody against SARS-CoV-2 spike protein using CDR-grafting combined with molecular simulation and machine learning.

PLoS Computational Biology · Apr 21, 2025Peer-reviewedBiophysics