Molecular BiologybioRxivPreprint
Borrelia burgdorferi infection-enhanced Ixodes scapularis serpins S12c5 and S13c5, target MASP1/3 to inhibit MBL-pathway complement activation and promote spirochete survival
Emily Bencosme-Cuevas, Tae Kim, Thu-Thuy Nguyen…·Albert Mulenga
This study identifies two tick serpins, S12c5 and S13c5, that inhibit complement activation and enhance Borrelia burgdorferi survival by targeting MASP1/3.
DOI 10.64898/2026.06.26.734773