Combining CRISPR/Cas mediated terminal resolution with a novel genetic workflow to achieve high diversity adenoviral libraries
Julian Fischer, Ariana Fedotova, Lena Jaki, Erwan Sallard, Anja Ehrhardt, Jonas Fuchs, Zsolt Ruzsics
The paper introduces a genetic workflow called HFR to construct high-diversity adenoviral libraries using CRISPR/Cas9 mediated terminal resolution.
Molecular Therapy — Methods & Clinical Development · Mar 18, 2024Peer-reviewedSynthetic Biology