Author

Christina Rye Underwood

AstraZeneca (United Kingdom)ORCID 0000-0002-2333-2177Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew F. JarnuczakiD· 1 shared Claire BerthaultiD· 1 shared Ghaith M. HamzaiD· 1 shared Kaushik SenguptaiD· 1 shared Kevin SaitoskiiD· 1 shared Maria RyaboshapkinaiD· 1 shared Raphaël ScharfmanniD· 1 shared Sèverine Pechberty· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBioinformatics

Andrew F. JarnuczakORCID

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1 paper

Recent·Most cited

Characterization of the secretome, transcriptome and proteome of human β cell line EndoC-βH1

Maria Ryaboshapkina, Kevin Saitoski, Ghaith M. Hamza, Andrew F. Jarnuczak, Sèverine Pechberty, Claire Berthault, Kaushik Sengupta, Christina Rye Underwood, Shalini Andersson, Raphaël Scharfmann

The paper validates EndoC-βH1 as a translational human β cell model using omics and characterizes its secretome, finding it secretes 671 proteins in baseline and 3,278 under stress, with exosome secretion as a major mode.

Molecular & Cellular Proteomics · Apr 1, 2022Peer-reviewedBioinformatics