Antonio Salas

Cross-species epigenomic signatures of exceptional longevity: Insights from Jonathan the Giant Tortoise and human centenarians

This study compares epigenomic signatures of longevity between a giant tortoise and humans, finding shared methylation patterns linked to telomere biology.

A reproducible buccal transcriptomic response to music exposure in autism spectrum disorder: insights into the oral-brain axis

The paper identifies a reproducible transcriptional response to music exposure in ASD using buccal samples, highlighting neuroimmune pathways and a two-gene signature for monitoring interventions.

Host gene-expression signatures accurately distinguish bacterial, viral, and inflammatory diseases in febrile children across multiple cohorts

The paper identifies host gene-expression signatures that distinguish bacterial, viral, and inflammatory diseases in febrile children across multiple cohorts, achieving high diagnostic accuracy.

A prospective multi-cohort study identifies reproducible molecular responses to musical stimulation in the human tear proteome

The paper identifies reproducible molecular responses in human tear proteomes to musical stimulation using proteomics and machine learning across two cohorts.

From prehistory to present-day: How isolation shaped the distinct genomic makeup of Italian Alpine valleys

This study examines the genomic makeup of modern Italian Alpine valleys, showing they retain ancient Neolithic ancestry and show microgeographic genetic subclusters shaped by isolation and drift.

Whole-genome sequencing in Galicia reveals male-biased pre-Islamic North African ancestry, subtle population structure, and micro-geographic patterns of disease risk

Decoding the peripheral transcriptomic and meta-genomic response to music in Autism Spectrum Disorder via saliva-based RNA sequencing

This study uses saliva-based RNA sequencing to explore how music affects gene expression and microbiota in individuals with autism spectrum disorder, identifying key genes and microbial shifts linked to neurodevelopmental and immune processes.

Music elicits different gene expression responses in the buccal cavity of age-related cognitive disorders patients and healthy controls

This paper shows that music affects gene expression in the buccal cavity differently in age-related cognitive disorder patients compared to healthy controls.

Harmonizing the oral-brain axis: Music-induced microbiota shifts in age-related cognitive disorders and healthy aging

This study shows that music can change the oral microbiome in people with age-related cognitive disorders, affecting both the types of microbes and their functions, which are linked to neurodegenerative processes.

Can music modulate gene expression involved in traumatic brain injury? An integrative transcriptomic and epigenomic proof of concept

This study investigates how music affects gene expression and methylation in traumatic brain injury by comparing transcriptomic and epigenomic data from healthy individuals and TBI patients.

Tuning gene expression to music: the compensatory effect of music on age-related cognitive disorders

This study examines how music affects gene expression in age-related cognitive disorders, finding that it modulates gene pathways linked to neurodegeneration and shows a compensatory effect compared to MCI/AD.

A multi-tissue study of immune gene expression profiling highlights the key role of the nasal epithelium in COVID-19 severity

The paper analyzes immune gene expression across nasal, buccal, and blood tissues to identify severity-related immune signatures in COVID-19 patients.

Archaeogenomic Distinctiveness of the Isthmo-Colombian Area

The paper analyzes genomic data from Indigenous groups in Panama to reveal pre-Hispanic demographic changes and the genetic structure of the Isthmo-Colombian area.

Haplocheck: Phylogeny-based Contamination Detection in Mitochondrial and Whole-Genome Sequencing Studies

Haplocheck detects contamination in mitochondrial and whole-genome sequencing studies using mitochondrial phylogeny, showing high concordance with nuclear DNA results.

The impact of super-spreaders in COVID-19: mapping genome variation worldwide

The paper analyzes >4,700 SARS-CoV-2 genomes to map global genetic variation and identify super-spreaders' impact on the pandemic.

Extraordinary claims require extraordinary evidence in the case of asserted mtDNA biparental inheritance

The paper reassesses claims of mtDNA biparental inheritance from Luo et al. (2018) and finds methodological issues and inconsistencies in their findings.