Valeria Nicolini

PD-1-Targeted IL-2v Expands a Novel Stem-like T Cell Subset Distinct from Anti-PD-1 Therapy to Enhance Effector Differentiation

This study shows PD1-IL2v expands a novel stem-like T cell subset in lymph nodes that enhances effector differentiation, distinct from PD-1 therapy's exhausted state.

From prehistory to present-day: How isolation shaped the distinct genomic makeup of Italian Alpine valleys

This study examines the genomic makeup of modern Italian Alpine valleys, showing they retain ancient Neolithic ancestry and show microgeographic genetic subclusters shaped by isolation and drift.

DNA Traces on the Shroud of Turin: Metagenomics of the 1978 Official Sample Collection

The paper analyzes DNA and metagenomic data from the 1978 Shroud of Turin samples, revealing human mtDNA lineages, microbial communities, and contaminants, while radiocarbon dating indicates repair events in the 16th and 17th centuries.

Ancient genomes from the siege and destruction of Middle Bronze Age Roca Vecchia (Apulia, Italy) shed light on Aegean contacts and conflicts

The paper analyzes ancient genomes from Roca Vecchia to determine genetic contributions from Minoans and local populations during the Bronze Age.