Background modeling, Quality Control and Normalization for GeoMx RNA data with GeoDiff
Lei Yang, Zhi Gang Yang, Patrick J. Danaher, Stephanie M. Zimmerman, TYLER D. HETHER, David Henderson, Joseph Beechem
The paper introduces a statistical model-based workflow for quality control and normalization of GeoMx RNA data, outperforming conventional methods in reducing background noise and technical variability.
bioRxiv · May 26, 2022 · PreprintBioinformatics