Author

Krishna Sriram

University of California San DiegoORCID 0000-0002-2385-3626Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:CITE-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Kevin MoyungiD· 2 shared Paul A. InseliD· 2 shared Andrew M. LowyiD· 1 shared Cristina SalmeróniD· 1 shared Hannah K. CarteriD· 1 shared Jordin Marucut· 1 shared Matthew William GorriD· 1 shared Randall P. French· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioinformatics

Kevin MoyungORCID

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2 papers

Recent·Most cited

GPCRs show widespread differential mRNA expression and frequent mutation and copy number variation in solid tumors

Krishna Sriram, Kevin Moyung, Ross Corriden, Hannah K. Carter, Paul A. Insel

This study examines GPCR expression, mutations, and copy number variation in solid tumors, finding widespread differential expression and frequent mutations, suggesting potential roles as biomarkers and targets.

PLoS Biology · Nov 25, 2019Peer-reviewedBioinformatics

Detection and quantification of GPCR mRNA: An assessment and implications of data from high-content methods

Krishna Sriram, Shu Z. Wiley, Kevin Moyung, Matthew William Gorr, Cristina Salmerón, Jordin Marucut, Randall P. French, Andrew M. Lowy, Paul A. Insel

The paper compares methods for detecting and quantifying GPCR mRNA expression, finding RNA-seq and TaqMan arrays outperform microarrays in accuracy and correlation with functional outcomes.

ACS Omega · Sep 30, 2019Peer-reviewedMolecular Biology