Cancer BiologybioRxivPreprint
Spatial multi-omics reveals targetable immunosuppressive macrophage T-cell interactions in human AML bone marrow
Merel van der Meulen, Emma S. Pool, Alicia Perzolli…·Olaf T Heidenreich
This paper uses spatial multi-omics to identify immunosuppressive interactions between AML, macrophages, and T cells in bone marrow, highlighting the Galectin-9 - CD44/TIM-3 axis as a therapeutic target.
DOI 10.64898/2026.08.07.743431