Systems BiologyProceedings of the National Academy of SciencesPeer-reviewed
Generation and analysis of context-specific genome-scale metabolic models derived from single-cell RNA-Seq data
Johan Gustafsson, Mihail Anton, Fariba Roshanzamir…·Jens Nielsen
The paper develops methods to generate context-specific genome-scale metabolic models from single-cell RNA-Seq data and shows that cell subtypes have unique metabolic profiles.