MicrobiologybioRxivPreprint
Particle Swarm Optimization with Random Forest Surrogates Modelling for Rational Design of Antimicrobial Fluoride Toothpaste Formulations against Clinically Significant Oral Pathogens
Clive Asuai, Oscar Whiliki, Andrew Mayor…·Ishiekwene Ekeoma Destiny
This paper optimizes antimicrobial toothpaste formulations using Particle Swarm Optimization with Random Forest surrogates, improving efficacy against oral pathogens while balancing cost and safety.
DOI 10.64898/2026.04.02.716085