Author

Haonan Feng

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-2559-1893Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Chong WuiD· 2 shared Lang Wu· 2 shared Peng WeiiD· 2 shared Arham SalmaniD· 1 shared Bingxin ZhaoiD· 1 shared Chad Daniel HuffiD· 1 shared Jia WuiD· 1 shared Jianjun J. ZhangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersGenetics

Chong WuORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintSep 30, 2026

Mendel, a foundation model of human genetic variation, prioritizes regulatory variants and improves gene expression prediction

Chong Wu, Arham Salman, Haonan Feng…·Wei Pan

Mendel is a foundation model trained on human whole genome sequences to prioritize regulatory variants and improve gene expression prediction.

DOI 10.64898/2026.09.28.755183

humanwhole-genome sequencing

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GenomicsNature CommunicationsPeer-reviewedNov 28, 2025

Benchmarking DNA Foundation Models for Genomic and Genetic Tasks

Haonan Feng, Lang Wu, Bingxin Zhao…·Chong Wu

This study benchmarks five DNA foundation models across genomic tasks, finding that mean token embeddings improve classification performance and specialized models outperform general ones in gene expression and QTL prediction.

53 citationstop 1%

whole-genome sequencingstatistical model

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