GenomicsbioRxivPreprint
The Limits of Haplotype-Based Approaches: Exploring the Applicability of the Li and Stephens Haplotype-Copying Model to Ancient Samples
Isabel Díaz‐Pinés Cort, Joshua Daniel Rubin, Peter Wad Sackett, Gabriel Renaud
This paper evaluates the Li and Stephens haplotype-copying model's performance on ancient DNA by using forward-simulated data and a constant-sized population model, finding it robust for haplotypes up to 900,000 years old.
DOI 10.1101/2023.06.21.545876