Leveraging epigenomes and three-dimensional genome organization for interpreting regulatory variation
Brittany A. Baur, Jacob Matthew Schreiber, Junha Shin, Shilu Zhang, Yi Zhang, Mohith Manjunath, Jun S. Song, William Stafford Noble, Sushmita Roy
The paper develops L-HiC-Reg to predict long-range regulatory interactions in new cell lines and applies it to interpret GWAS SNPs in complex diseases.
PLoS Computational Biology · Jul 10, 2023Peer-reviewedBioinformatics