Membrane channel hypothesis of lysosomal permeabilization by beta-amyloid
Dmitry V. Zaretsky, Maria V. Zaretskaia, Yaroslav I. Molkov
The paper proposes a hypothesis that amyloid-beta fragments form membrane channels in lysosomes, leading to lysosomal permeabilization and potential cell death through macromolecule leakage.
Neuroscience Letters · Nov 9, 2021Peer-reviewedNeuroscience