Yaroslav I. Molkov

The paper investigates synaptic interactions in the preBotzinger Complex using in vitro recordings, revealing a simplified inhibitory connectome compared to in situ conditions.

The paper develops a dual-rate model of motor adaptation to determine optimal practice schedules and shows reinforcement learning can recover these schedules under partial observability.

This study investigates speed-dependent turning strategies in quadrupedal locomotion using computational modeling, finding that different strategies excel at different speeds and that forelimbs primarily steer while hindlimbs adjust propulsion.

The paper investigates ionic mechanisms underlying bistability in spinal motoneurons using a computational model and mouse recordings, identifying key currents involved in plateau potentials and bistable firing.

The paper introduces a method to infer synaptic conductances from neuronal recordings and applies it to respiratory CPG circuits in rat brainstem.

This study develops a mathematical model of mouse locomotion to investigate the roles of sensory feedback and central interactions in gait control.

This study uses computational models to explore KF activity dynamics and their role in normal breathing and Rett syndrome-like respiratory patterns.

The paper tests and confirms three predictions of a biophysical model of the mammalian respiratory oscillator using optogenetic and pharmacological manipulations in neonatal mouse slices.

The paper proposes a hypothesis that amyloid-beta fragments form membrane channels in lysosomes, leading to lysosomal permeabilization and potential cell death through macromolecule leakage.

The paper investigates how heartbeats influence breathing through baroreceptor-mediated modulation of expiratory activity in both humans and rodent models.

This paper investigates the organization of locomotor CPG circuits by testing a hypothesis about state-dependent changes in rhythm generator operation using experimental and mathematical modeling approaches.

The paper re-examines the roles of INaP and ICAN in respiratory rhythm generation using a new computational model, finding that ICAN affects amplitude while INaP drives rhythm.