Author

Kaito Kobayashi

Artificial Intelligence Research CenterORCID 0000-0002-2662-2452Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:protein sequence· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Hayao TaguchiiD· 1 shared Hiroyuki NakaiiD· 1 shared Hisaka Shimizu· 1 shared Kazuki MaedaiD· 1 shared Kouji KuramochiiD· 1 shared Masahiro NakajimaiD· 1 shared Masumi Kageyama· 1 shared Miho Masuhiro· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

Hayao TaguchiORCID

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2 papers

Recent·Most cited

Data-efficient protein mutational effect prediction with weak supervision by molecular simulation and protein language models

Teppei Deguchi, Nur Syatila Ab Ghani, Yoichi Kurumida, Shinji Iida, Kaito Kobayashi, Yutaka Saitō

The paper presents a method that improves protein mutational effect prediction with limited experimental data by combining molecular simulation and protein language models.

Briefings in Bioinformatics · Aug 31, 2025Peer-reviewedBioinformatics

A beta-Galactosidase acting on unique galactosides: the structure and function of a beta-1,2-galactosidase from Bacteroides xylanisolvens, an intestinal bacterium

Yutaka Nakazawa, Masumi Kageyama, Tomohiko Matsuzawa, Ziqin Liang, Kaito Kobayashi, Hisaka Shimizu, Kazuki Maeda, Miho Masuhiro, Sei Motouchi, Saika Kumano, Nobukiyo Tanaka, Kouji Kuramochi, Hiroyuki Nakai, Hayao Taguchi, Masahiro Nakajima

This study identifies a beta-galactosidase from Bacteroides xylanisolvens that hydrolyzes beta-1,2-galactooligosaccharides, revealing its unique substrate specificity through structural and biochemical analysis.

Communications Biology · Jan 16, 2025Peer-reviewedBiochemistry