Decoding Mechanisms of PTEN Missense Mutations in Cancer and Autism Spectrum Disorder using Interpretable Machine Learning Approaches
Miao Yang, Jingran Wang, Ziyun Zhou, Wentian Li, Gennady M. Verkhivker, Fei Xiao, Guang Hu
This study uses interpretable machine learning and structural dynamics to analyze PTEN mutations linked to cancer and autism, revealing shared molecular mechanisms.
bioRxiv · Jan 16, 2025 · PreprintBioinformatics