Wentian Li

This study examines how APOE and TREM2 variants influence plasma levels of GFAP and NEFL in UK Biobank participants, finding age-dependent effects and associations with dementia risk.

This study uses interpretable machine learning and structural dynamics to analyze PTEN mutations linked to cancer and autism, revealing shared molecular mechanisms.

The paper identifies 113 craniosynostosis genes, finding that 21 are cancer driver genes, a 14-fold enrichment compared to baseline, and explores their shared roles in signaling pathways.

The paper compares alignment-free and alignment-based methods for detecting NUMTs in the human genome, finding that alignment-free methods detect additional NUMTs potentially more ancestral than those found by BLAST.

This study applies t-SNE to human genetic data, showing it can reveal population stratification at different scales, similar to PCA but more robust to outliers.