Nikolaos Sfakianakis

Modelling phenotypic plasticity in cancer invasion and metastasis: from microscopic interactions to macroscopic dynamics

This study develops macroscopic models to simulate cancer cell invasion and metastasis by bridging microscopic cell dynamics with continuum descriptions, showing accurate reproduction of phenotypic and spatial patterns.

Force-Dependent Cell-Cell Adhesion Dynamics in a Stochastic Regime for Cancer Invasion

The paper extends a cancer invasion model by incorporating stochastic N-cadherin bond lifetimes dependent on pulling force, predicting reduced motility and a transition between catch- and slip-bond behavior.

Modelling cancer cell dormancy in mice: statistical distributions predict reactivation times and survival dynamics

This study models cancer cell dormancy in mice using statistical distributions to predict reactivation times and survival dynamics, finding heavy-tailed and asymmetric distributions best fit dormancy patterns.