Erin R. Claussen

DirectContacts2: A network of direct physical protein interactions derived from high-throughput mass spectrometry experiments

DirectContacts2 identifies direct protein interactions using mass spectrometry data and machine learning, improving accuracy over existing resources and providing structural models for disease-related complexes.

hu.MAP3.0: Atlas of human protein complexes by integration of > 25,000 proteomic experiments

Machine learning integration of over 25,000 mass spectrometry experiments yields 15,326 human protein complexes covering 13,769 proteins, plus 511 AlphaFold-derived mutually exclusive subunit pairs.