Author

Chi Zhang

Yale UniversityORCID 0000-0002-2682-4142Unclaimed ORCID profile · follow to get notified of new preprints

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Chi Zhang11 papers · Shanghai Jiao Tong University

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Assay:GWAS summary statistics· 2 Approach:statistical model· 2 Research Focus:GWAS / association mapping· 1 Research Focus:polygenic risk· 1

Frequent Co-Authors

Hongyu ZhaoiD· 2 shared Geyu ZhouiD· 1 shared Tianqi Chen· 1 shared Yiliang ZhangiD· 1 shared Yunxuan ZhangiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

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2 shared papersGenetics

Hongyu ZhaoORCID

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2 papers

Recent·Most cited

Joint Modeling of Effect Sizes for Two Correlated Traits: Characterizing Trait Properties to Enhance Polygenic Risk Prediction

Chi Zhang, Geyu Zhou, Tianqi Chen, Hongyu Zhao

This study introduces PleioSDPR, a method that improves polygenic risk prediction by jointly modeling genetic effects across correlated traits, showing significant accuracy gains in real trait applications.

PLoS Genetics · Jan 26, 2026Peer-reviewedGenetics

Benchmarking local genetic correlation estimation methods using summary statistics from genome-wide association studies

Chi Zhang, Yiliang Zhang, Yunxuan Zhang, Hongyu Zhao

This study benchmarks three methods for estimating local genetic correlation using GWAS summary statistics, highlighting challenges with sample overlap and LD estimation.

Briefings in Bioinformatics · Sep 22, 2023Peer-reviewedGenetic & Genomic Medicine