Race- and sex-specific disease trajectory in individuals with rare variants in seven cerebrovascular small vessel disease genes: a genotype-first population study
Jiang Li, Vida Abedi, Durgesh Prasad Chaudhary, Oded Goren, David J. Carey, Karen E. Wain, Ramin Zand
This study identifies race- and sex-specific increased risks of cerebrovascular and circulatory diseases in carriers of seven monogenic CSVD risk genes using a genotype-first approach in a large biobank cohort.
medRxiv · Aug 11, 2022 · PreprintGenetic & Genomic Medicine