Familial primary ovarian insufficiency associated with a SYCE1 point mutation: Defective meiosis elucidated in humanized mice
Diego Hernández-López, Adriana Geisinger, María Fernanda Trovero, Federico F. Santiñaque, M. Mónica Brauer, Gustavo A. Folle, Ricardo Benavente, Rosana Rodríguez‐Casuriaga
This study confirms a SYCE1 mutation causes infertility in humanized mice, revealing synapsis defects as the molecular mechanism.
Molecular Human Reproduction · May 7, 2020Peer-reviewedGenetics