Author

Laura Guio

ORCID 0000-0002-2734-4909Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:long-read sequencing· 1 Approach:machine learning (classical)· 1 Assay:scRNA-seq· 1 Assay:snRNA-seq· 1

Frequent Co-Authors

Andrés Naranjo· 2 shared Danilo Alejandro García OrjuelaiD· 2 shared Jennifer Julieth Guzmán-Porras· 2 shared Jorge Díaz-RiañoiD· 2 shared Jorge DuitamaiD· 2 shared Melissa RoblesiD· 2 shared Paula Siaucho· 2 shared Adolfo J. QuiróziD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersNeuroscience

Andrés Naranjo

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2 papers

Recent·Most cited

Single Cell Transcriptomics of Refractory Epilepsy patients in Colombia

Jorge Díaz-Riaño, Juan Pablo Carvajal-Dossman, Laura Guio, Daniel Mahecha, Paula Siaucho, Jennifer Julieth Guzmán-Porras, Melissa Robles, Lina Bejarano, Paula Guzmán-Sastoque, Danilo Alejandro García Orjuela, Andrés Naranjo, Óscar Zorro, Silvia Maradei, Jorge Duitama

This study analyzes single-cell transcriptomics data from five pediatric refractory epilepsy patients in Colombia, identifying glia-driven dysregulation and neuroinflammatory processes.

bioRxiv · Mar 12, 2026 · PreprintNeuroscience

New algorithms for unsupervised cell clusteringfrom scRNA-seq data

Melissa Robles, Jorge Díaz-Riaño, Cristhian Forigua, Sebastian Ojeda, Laura Guio, Paula Siaucho, Jennifer Julieth Guzmán-Porras, Danilo Alejandro García Orjuela, Andrés Naranjo, Silvia Juliana Maradei Anaya, Adolfo J. Quiróz, Jorge Duitama

This paper introduces new algorithms for clustering scRNA-seq data, showing competitive accuracy and highlighting factors affecting performance.

Bioinformatics Advances · Jan 1, 2026Peer-reviewedBioinformatics