Author

Paula Guzmán-Sastoque

Universidad de Los AndesORCID 0009-0004-2201-0100Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:long-read sequencing· 1 Assay:metabolomics· 1 Assay:snRNA-seq· 1

Frequent Co-Authors

Andrés Naranjo· 1 shared Carolina Muñoz-CamargoiD· 1 shared Chad LeidyiD· 1 shared Chiara CarazzoneiD· 1 shared Christian FuertesiD· 1 shared Daniel Mahecha· 1 shared Danilo Alejandro García OrjuelaiD· 1 shared Elizabeth Suesca· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Andrés Naranjo

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Exposure to the antimicrobial peptides LL-37 and ATRA-1 induces a lipidome response in Staphylococcus aureus that alters membrane biophysical properties

Christian Fuertes, Juan E. Gonzalez, Elizabeth Suesca, Paula Guzmán-Sastoque, Carolina Muñoz-Camargo, Marcela Manrique-Moreno, Chiara Carazzone, Chad Leidy

This study investigates how antimicrobial peptides LL-37 and ATRA-1 alter lipid composition and membrane biophysical properties in Staphylococcus aureus, revealing peptide-specific lipid remodeling responses.

Biochimica et Biophysica Acta (BBA) - Biomembranes · Jun 16, 2026Peer-reviewedBiophysics

Single Cell Transcriptomics of Refractory Epilepsy patients in Colombia

Jorge Díaz-Riaño, Juan Pablo Carvajal-Dossman, Laura Guio, Daniel Mahecha, Paula Siaucho, Jennifer Julieth Guzmán-Porras, Melissa Robles, Lina Bejarano, Paula Guzmán-Sastoque, Danilo Alejandro García Orjuela, Andrés Naranjo, Óscar Zorro, Silvia Maradei, Jorge Duitama

This study analyzes single-cell transcriptomics data from five pediatric refractory epilepsy patients in Colombia, identifying glia-driven dysregulation and neuroinflammatory processes.

bioRxiv · Mar 12, 2026 · PreprintNeuroscience