Author

Jesús Lacal

Universidad de SalamancaORCID 0000-0002-2751-7291Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

María Isidoro‐GarcíaiD· 2 shared Pablo Prieto‐MatosiD· 2 shared Alessio CoppolaiD· 1 shared Ana Maria PaladeiD· 1 shared D.H. Heredero JungiD· 1 shared Elena Marcos-VadilloiD· 1 shared Juan Báez-FloresiD· 1 shared Kenza CherietiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

María Isidoro‐GarcíaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintJul 13, 2026

An integrated computational, clinical, and functional framework for assessing PTPN11 (SHP2) variant effects on ERK signaling and neural crest cell behavior in Noonan spectrum disorders

Mario Rodríguez-Martín, Kenza Cheriet, Sandrine Adiba…·Pablo Prieto‐Matos

The paper assesses PTPN11 variant effects on ERK signaling and neural crest cell behavior in Noonan spectrum disorders through clinical, biochemical, and in vivo analyses.

DOI 10.64898/2026.07.09.26357683

humanproteomics

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintJul 9, 2026

SPRED1 variants reveal differential impacts on signaling dynamics

Juan Báez-Flores, Alessio Coppola, Noemi Ferrito…·Pablo Prieto‐Matos

The paper functionally assesses SPRED1 variants to determine their impact on RAS-MAPK signaling dynamics and clinical phenotypes.

DOI 10.64898/2026.07.08.26357239

humanproteomics

𝕏 PostBluesky