SLAMF7 and SLAMF8 receptors shape human plasmacytoid dendritic cell responses to intracellular bacteria
Joaquín Miguel Pellegrini, Anne Keriel, Laurent Gorvel, Sean B. Hanniffy, Vilma Arce Gorvel, Mile Bosilkovski, Javier Solera, Stéphane Méresse, Sylvie Mémet, Jean‐Pierre Gorvel
This study identifies SLAMF7 and SLAMF8 as key regulators of human pDC responses to intracellular bacteria, showing their role in modulating type I IFN production and mitochondrial ROS levels.
Journal of Clinical Investigation · Apr 14, 2025Peer-reviewedImmunology