Molecular BiologyNature CommunicationsPeer-reviewed
Noncanonical roles of chemokine regions in CCR9 activation revealed by structural modeling and mutational mapping
Inês Pinheiro, John R.D. Dawson, Nicolas Calo…·Oliver Hartley
This study identifies a non-canonical activation mechanism of CCR9 by CCL25 through structural modeling and mutational analysis, revealing the 30s loop as the key activation region.
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