Author

John O’Brien

University of KentuckyORCID 0000-0002-2889-1998Unclaimed ORCID profile · follow to get notified of new preprints

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John O’Brien1 paper

Biology Disciplines

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Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Brianna M. DorattiD· 1 shared Cynthia CockerhamiD· 1 shared Delphine C. MalherbeiD· 1 shared Heather TrueiD· 1 shared Ilhem MessaoudiiD· 1 shared Mahdi Eskandarian BoroujeniiD· 1 shared Nathan R. ShelmaniD· 1 shared Sheridan B. Wagner· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperImmunology

Brianna M. DorattORCID

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1 paper

Recent·Most cited

Maternal opioid use with and without hepatitis C infection disrupts the structure and immune landscape of the maternal-fetal interface

Heather True, Brianna M. Doratt, Sheridan B. Wagner, Delphine C. Malherbe, Nathan R. Shelman, Mahdi Eskandarian Boroujeni, Cynthia Cockerham, John O’Brien, Ilhem Messaoudi

This study investigates how maternal opioid use disorder with and without hepatitis C infection affects placental structure, immune function, and cell-cell communication.

bioRxiv · Jul 30, 2025 · PreprintImmunology