Highly specific, multiplexed isothermal pathogen detection with fluorescent aptamer readout
Lauren M. Aufdembrink, Pavana Khan, Nathaniel J. Gaut, Katarzyna P. Adamala, Aaron E. Engelhart
This paper introduces Apta-NASBA, a method for highly specific, multiplexed pathogen detection using fluorescent aptamers, achieving a 1 pM detection limit and compatible with various detection platforms.
RNA · Jun 1, 2020Peer-reviewedSynthetic Biology