Prediction of metabolites associated with somatic mutations in cancers by using genome-scale metabolic models and mutation data
GaRyoung Lee, Sang Mi Lee, Sungyoung Lee, Chang Wook Jeong, Hyojin Song, Sang Yup Lee, Hongseok Yun, Youngil Koh, Hyun Uk Kim
The paper develops a computational workflow to predict metabolite-gene-pathway associations in cancers using genome-scale metabolic models and mutation data, showing significant associations with specific somatic mutations.
Genome biology · Mar 11, 2024Peer-reviewedSystems Biology