Sang Yup Lee

The paper introduces FROG analysis to standardize reproducibility assessments of genome-scale metabolic models, resulting in full reproducibility of all tested models.

The paper develops a computational workflow to predict metabolite-gene-pathway associations in cancers using genome-scale metabolic models and mutation data, showing significant associations with specific somatic mutations.

Memote, open-source Python software, runs a community-maintained, partly scored test suite (consistency, biomass, annotations, optional experimental data) on SBML-encoded genome-scale metabolic models, once or through continuous integration.

The paper develops CRISPR-BEST, a DSB-free base editing system for filamentous actinomycetes, achieving single-nucleotide resolution in Streptomyces species.

This paper introduces a yeast platform for producing bacterial aromatic polyketides using a synthetic polyketide synthase system.