Rab27 GTPases regulate alpha-synuclein uptake, cell-to-cell 1 transmission, and toxicity
Rachel Underwood, Bing Wang, Aneesh Pathak, Laura A. Volpicelli‐Daley, Talene A. Yacoubian
This study shows Rab27a/b knockout prevents alpha-synuclein aggregation, toxicity, and cell-to-cell transmission in vitro and in vivo.
bioRxiv · Nov 17, 2020 · PreprintNeuroscience