Decoupling growth and production by removing the origin of replication from a bacterial chromosome
Marje Kasari, Villu Kasari, Mirjam Kärmas, Arvi Jõers
This paper describes a method to decouple bacterial growth and production by permanently removing the origin of replication, enabling continued protein synthesis without growth.
ACS Synthetic Biology · Jul 7, 2022Peer-reviewedSynthetic Biology