Development of a Quantitative Systems Pharmacology Model to Interrogate Mitochondrial Metabolism in Heart Failure
Lyndsey F. Meyer, Neda Nourabadi, Cynthia J. Musante, Daniel Andrew Beard, Anna Sher
This paper develops a quantitative systems pharmacology model to study mitochondrial metabolism in heart failure and predicts how changes in metabolic pathways affect exercise capacity.
bioRxiv · Jul 8, 2025 · PreprintSystems Biology