PAC-MAP: Proximity Adjusted Centroid Mapping for Accurate Detection of Nuclei in Dense 3D Cell Systems
Tim Van De Looverbosch, Sarah De Beuckeleer, Frederik De Smet, Jan Sijbers, Winnok Harald De Vos
PAC-MAP improves nucleus detection in dense 3D cell systems by predicting centroid positions and proximity, achieving high recall and F1 scores in spheroids and organoids.
bioRxiv · Jul 18, 2024 · PreprintBioinformatics