Donghyuk Kim

The paper introduces ChIP-mini, a low-input ChIP-exo method, to study DNA-binding protein dynamics in Salmonella Typhimurium within macrophages, revealing H-NS and RpoD binding sites and their roles in virulence gene transcription.

The paper investigates how post-translational modifications in Escherichia coli regulate metabolic adaptation to environmental changes, showing their impact on fitness and pathway usage.

The paper integrates ChIP-exo and RNA-seq data to identify Cra's binding sites and regulon genes in E. coli, revealing its role in optimizing growth on poor carbon sources through metabolic regulation.