Rescue of neurogenesis and age-associated cognitive decline in SAMP8 mouse: role of transforming growth factor alpha
Ricardo Gómez‐Oliva, Sergio Martínez‐Ortega, Isabel Atienza‐Navarro, Samuel Domínguez‐García, Carlos Bernal Utrera, Noelia Geribaldi‐Doldán, Cristina Verástegui, Abdellah Ezzanad, Rosario Hernández‐Galán, Pedro Nunez‐Abades, Mónica Garcı́a-Alloza, Carmen Castro
This study shows that targeting TGF-alpha release rescues neurogenesis and cognitive decline in SAMP8 mice, suggesting it as a potential therapeutic strategy for age-related neurological disorders.
Aging Cell · May 12, 2023Peer-reviewedNeuroscience