Mechanistic Insights into Sphingomyelin Nanoemulsions as Drug Delivery Systems for Non-Small Cell Lung Cancer Therapy
Emma Ramos Docampo, Jenifer García-Fernández, Inés Mármol, Irene Morín-Jiménez, Maria Iglesias Baleato, María de la Fuente
This study investigates the cytotoxic effects and mechanisms of sphingomyelin nanoemulsions on A549 cells, showing they induce apoptosis through lysosomal and mitochondrial damage and enhance cytotoxicity when loaded with resveratrol.
Pharmaceutics · Apr 2, 2025Peer-reviewedPharmacology & Toxicology