Author

Luc Letenneur

InsermORCID 0000-0002-3274-937XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 4 Approach:statistical model· 4 Research Focus:GWAS / association mapping· 2 Assay:GWAS summary statistics· 2 Research Focus:variant calling· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Anne BolandiD· 4 shared Benjamin Grenier‐BoleyiD· 4 shared Jean‐François DeleuzeiD· 4 shared Camille Charbonnier-Le Clézio· 3 shared Céline BellengueziD· 3 shared Christian Dina CiD· 3 shared Claude FéreciD· 3 shared Delphine Bacq· 3 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersGenetics

Anne BolandORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

SURFBAT: a surrogate family-based association test building on large imputation reference panels

Anthony F. Herzig, Simone Rubinacci, Gaëlle Marenne, Hervé Perdry, Emmanuelle Génin, Dominique Campion, Jean‐François Dartigues, Jean‐François Deleuze, Jean‐Charles Lambert, Richard Redon, Thomas E Ludwig, Benjamin Grenier‐Boley, Sébastien Letort, Pierre Lindenbaum, Vincent Meyer, , Olivier Delaneau

SURFBAT approximates transmission-disequilibrium tests using imputed haplotypes to detect genotype-phenotype associations while being robust to population stratification.

G3 Genes Genomes Genetics · Dec 9, 2024Peer-reviewedGenetics

Can imputation in a European country be improved by local reference panels? The example of France

Anthony F. Herzig, Lourdes Velo‐Suárez, Principal Investigators, Dominique Campion, Jean‐François Dartigues, Jean‐Charles Lambert, Collaborators, Bioinformatics, Thomas Ludwig, Benjamin Grenier‐Boley, Sébastien Letort, Pierre Lindenbaum, Vincent Meyer, Olivier Quenez, Statistical genetics, , Emmanuelle Génin

The paper evaluates whether using a local reference panel improves imputation accuracy in French individuals compared to a public reference panel, showing benefits of combining both approaches.

Scientific Reports · Jan 3, 2024Peer-reviewedGenetics

Integrated Clinical and Omics Approach to Rare Diseases: Novel Genes and Oligogenic Inheritance in Holoprosencephaly

Artem Kim, Clara Savary, Christèle Dubourg, Wilfrid Carré, Charlotte Mouden, Houda Hamdi‐Rozé, Hélène Guyodo, Jérôme Le Douce, Emmanuelle Génin, Dominique Campion, Jean‐François Dartigues, Jean‐François Deleuze, Jean‐Charles Lambert, Richard Redon, Thomas E Ludwig, , Tania Attié‐Bitach

This study identifies novel HPE genes and oligogenic inheritance patterns in holoprosencephaly by integrating clinical data with exome sequencing and gene prioritization.

Brain · Oct 29, 2018Peer-reviewedGenetics

Analysis of shared heritability in common disorders of the brain

Verneri Anttila, Brendan K Bulik-Sullivan, Hilary K. Finucane, Raymond Kenney Walters, José Brás, Laramie E. Duncan, Valentina Escott‐Price, Guido J. Falcone, Padhraig Gormley, Rainer Malik, Nikolaos A. Patsopoulos, Stephan Ripke, Zhi Wei, Dongmei Yu, Phil Hyoun Lee, , Nicholas A. Furlotte

Genetic correlations across 25 brain disorders (215,683 cases) reveal broad psychiatric common-variant sharing, largely distinct neurological disorders, and migraine as the only significant cross-category link.

Science · Jun 21, 2018Peer-reviewedGenetics✦ In-depth digest