Predicting the Outcomes of New Short-Course Regimens for Multi-Drug Resistant Tuberculosis Using Intrahost and Pharmacokinetic-Pharmacodynamic Modelling
Tan Nhut Doan, Pengxing Cao, Theophilus I. Emeto, James M. McCaw, Emma Sue McBryde
The paper uses mathematical models to predict that short-course bedaquiline regimens could reduce MDR-TB treatment to 18 weeks with high success rates.
Antimicrobial Agents and Chemotherapy · Sep 24, 2018Peer-reviewedSystems Biology