DNA Methyltransferase Inhibitors with Novel Chemical Scaffolds
K. Eurídice Juárez‐Mercado, Fernando Daniel Prieto-Martínez, Norberto Sánchez‐Cruz, Andrea Peña‐Castillo, Diego Prada‐Gracia, José L. Medina‐Franco
The paper identifies five DNMT1 inhibitors, including theaflavin, glyburide, and panobinostat, and validates their activity through enzymatic assays and molecular docking.
bioRxiv · Oct 13, 2020 · PreprintSystems Biology