Molecular BiologyPLoS GeneticsPeer-reviewed
Depletion of Ric-8B leads to reduced mTORC2 activity
Maíra H. Nagai, Luciana M. Gutiyama, Victor P. S. Xavier…·Bettina Malnic
This study shows that Ric-8B hypomorphism reduces mTORC2 activity in mice, leading to embryonic defects and impaired GPCR/G protein signaling.
5 citations