Elisa R. Donnard

TEscape uses long-read sequencing to comprehensively annotate the human transposable element transcriptome, identifying over 83,000 previously unannotated isoforms.

This study uses single-cell RNA sequencing to analyze a FXS mouse model, revealing cell-type specific dysregulation and potential mTOR pathway differences.

This study shows FMRP stabilizes mRNAs with optimal codons in neurons, linking codon usage to mRNA stability and contributing to FXS pathogenesis.

The paper creates a single-cell atlas of the murine epididymis and vas deferens, identifying cell types and their regional specialization, and revealing potential signaling networks.

This study shows that Ric-8B hypomorphism reduces mTORC2 activity in mice, leading to embryonic defects and impaired GPCR/G protein signaling.

The paper uses single-cell RNA sequencing to study influenza infection in human nasal washes, identifying a novel goblet cell population and tracking viral variation across infected individuals.

The paper uses ribosome profiling and RNA-Seq in budding yeast to analyze the translational effects of tRNA modifications, identifying new roles in gene regulation and retroelement control.