Robyn P. Araujo

This paper develops an agent-based model to simulate multiple sclerosis progression and evaluates therapeutic strategies targeting oligodendrocytes and the blood-brain barrier.

The paper provides a systems-level description of retinal cholesterol homeostasis through a chemical reaction network and identifies integral control mechanisms regulating cholesterol in the human retina.

The paper identifies design principles for Robust Perfect Adaptation in biochemical networks, showing they can be decomposed into two modular building blocks.

This study introduces two new models of covalent modification cycles with positive autoregulation, showing that simplifications using Michaelian approximations fail to capture the full range of signaling behaviors.

This paper analyzes ODE-based biochemical models with singular Jacobians, deriving an adaptation condition applicable to both single and multiple input-output systems.