Author

Shane L. Hubler

University of MinnesotaORCID 0000-0002-3401-8589Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:deconvolution· 1 Assay:proteomics· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Caleb EasterlyiD· 1 shared James E. JohnsoniD· 1 shared Pratik Dilip JagtapiD· 1 shared Praveen KumariD· 1 shared Subina MehtaiD· 1 shared Timothy J. GriffiniD· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBioinformatics

Caleb EasterlyORCID

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1 paper

Recent·Most cited

BioinformaticsJournal of Proteome ResearchPeer-reviewedDec 3, 2019

Challenges in Peptide-Spectrum Matching: a Robust and Reproducible Statistical Framework for Removing Low-Accuracy, High-Scoring Hits

Shane L. Hubler, Praveen Kumar, Subina Mehta…·Timothy J. Griffin

The paper introduces PMD-FDR, a Bayesian confidence measure to filter high-scoring but likely false peptide-spectrum matches in proteomics, improving accuracy in standard, proteogenomics, and metaproteomics datasets.

14 citations

proteomicsstatistical model

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