NeurosciencebioRxivPreprint
Multi-site Cleavage of Amyloid-β by a Minimal 5-mer Catalytic Peptide: Mimicking Serine Protease Activity via Hydrophobic Anchoring
Fumiaki Ito, Motomi Konishi, Rina Nakamura, Toshifumi Akizawa
This study investigates how the pentapeptide SKGQA cleaves multiple sites on amyloid-beta by using hydrophobic anchoring and stochastic catalytic targeting.
DOI 10.64898/2026.06.03.729455