Genotoxicity evaluation of levonorgestrel-releasing intrauterine system (LNG-IUS) in exfoliated cervical cells using the micronucleus (MN) test
Ayşe Gül Zamanı, Rengin Karataylı, Kazım Gezginç, Aynur Acar, Mahmut Selman Yıldırım
This study evaluates the genotoxicity of LNG-IUS by analyzing micronuclei and other nuclear anomalies in cervical cells before and after insertion, finding no significant increase in micronuclei but increased cytotoxicity-related changes.
medRxiv · Jul 8, 2021 · PreprintGenetic & Genomic Medicine